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Amgen Bone Health Mentoring Program
Monday, October 15, at 11:30am – 2:30pm ◼ Ruth Chris, Minneapolis, MN
1028 Effects of Odanacatib on the Distal Radius and
Tibia in Postmenopausal Women: Improvements in
cortical geometry and estimated bone strength.
Papp A, Cheung A, Majumdar S, et al.
Session: Concurrent Oral Session 05: John H. Carsten's
Memorial Session for Osteoporosis Treatment ◼
Saturday , October 13, 10:15 AM - 10:30 AM ◼
Auditorium-Main/Minneapolis Convention Center
Objective Abstract Information Additional Notes from
Methods Poster/Presentation*
▪ Based on previous studies with ODN,
this study determined the effect of Strengths, Weaknesses, Key
ODN on cortical geometry and bone Points
strength.
▪ Randomized, double-blind placebo-
controlled trial among 214 PM
women with baseline lumbar spine T-
score -1.81 i0.83.
▪ Patients were randomized to receive
oral ODN 50 mg or weekly placebo
for 2 years.
▪ Primary end-point: % change from
baseline in LS BMD at 1 year.
* Assignment notes will be collected at the Amgen Mentoring Program Debrief Meeting. Hardcopy or Electronic versions are acceptable
